Dr. Doug Thamm discusses the development and use of Tanovea, a drug for treating lymphoma in dogs. He explains the drug's origins, initially researched as a human cancer therapeutic in collaboration with Gilead Sciences, and its transition to veterinary use.  

Dr. Thamm provides insights into Tanovea’s application, dosage, and effectiveness compared to the CHOP protocol, as well as its potential side effects and other possible uses in different cancer types like multiple myeloma. The episode also delves into related immunotherapy research and personal reflections from Dr. Thamm, a double cancer survivor, on his career choice in veterinary oncology.

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Related Videos: 

https://www.youtube.com/watch?v=G0iRyKshzq8 

Related Links: 

Our article on lymphoma: https://www.dogcancer.com/articles/types-of-dog-cancer/lymphoma-in-dogs/ 

Our article on Tanovea: https://www.dogcancer.com/articles/drugs/tanovea-rabacfosadine-chemotherapy/ 

Get the facts on dog cancer remission: https://www.dogcancer.com/articles/stats-and-facts/dog-cancer-remission/ 

Chapters: 

00:00 Introduction 

00:13  Interview with Dr. Doug Thamm 

00:26  The Early Involvement with Tanovea 

00:41  Challenges and Discoveries in Drug Development 

02:16  Transition from Human to Veterinary Use 

02:48  Clinical Trials and Dosage Experiments 

06:45  FDA Approval and Practical Use 

08:05  Comparing Tanovea and CHOP Protocol 

15:23  Exploring Alternative Treatments: Laverdia 

18:43  Off-Label Uses and Future Research 

23:46  Exploring Tanovea's Effectiveness in Blood Cancers 

25:14  Cost Comparison: Tanovea vs. CHOP 

26:15  Side Effects of Tanovea 

28:47  Pulmonary Fibrosis and Breed-Specific Risks 

32:52  Personal Cancer Journeys: Dr. Doug and His Wife 

38:23  Debunking Myths About Dog Cancer Treatment 

42:24  The Future of Cancer Treatment: Immunotherapy 

45:23  Conclusion and Resources 

Get to know Dr. Doug Thamm:

https://www.dogcancer.com/people/doug-Thammm-v-m-d-diplomate-acvim-oncology/  

For more details, articles, podcast episodes, and quality education, go to the episode page: https://www.dogcancer.com/podcast/  

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